Cardiomyopathies

Cardiovascular:  16% of Blueprint

 Dilated Cardiomyopathy

  • Key features: Systolic dysfunction-EF<50%. Gradual CHF-mostly dyspnea.
  • Causes: Often Idiopathic, chronic alcohol, postpartum, myocarditis, chronic tachycardia, Amloidosis, Sarcoidosis, Hemochromatosis, R ventricular Dysplasia, NOT related to ischemic heart disease, HTN, nor Valvular disease

 

1)   H&P: rales, elevated JVP, cardiomegaly, S3 gallop rhythm, often murmurs of functional mitral or tricuspid regurgitation, peripheral edema, or ascites. pulsus alternans (variation of amplitude in every other beat on an art-line), pallor, and cyanosis,

2)   Lab and diagnostic studies:

            -ECG: low voltage, Sinus tachycardia, LBBB, Ventricular or atrial arrhythmias

            -CXR: cardiomegaly, pulmonary congestion, Pleural effusions[R>L]

            -Doppler Echo: LV dilation, thinning, and global dysfunction

            -Stress test: May suggest underlying disease

            -MRI: helpful in infiltrative disease

3)   Key words/Pathognomonic-

4)   Treatment: Not much, stop alcohol, treat hyper/hypothyroidism, acromegaly, pheochromocytoma, treat CHF, Long term anticoagulation, consider bivent pacer, ICD in EF<35%, transplant, immunosuppressive Tx NOT indicated.

5)   Pharmacology: Treat CHF; diuretics and beta-blockers, ACE inhibitors, Aldosterone inhibitors  

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